At head of title: C.177.M.49.1924.III.(C.H.193)
|Statement||first report by Kiyoshi Shiga, H. Kawamura and K. Tsuchiya.|
|Contributions||Shiga, Kiyoshi, 1870-|
|The Physical Object|
|Pagination||71 p. table, diag.|
|Number of Pages||71|
Standardization of Anti-Dysentery (Shiga) Serum * H. J. Sudmersen, B. F. Runge, and R. A. O'Brien * The substance of the present paper is to be presented as the first of a series of reports to the League of Nations Standardization Committee, which has requested workers in a number of different laboratories to investigate the : H. J. Sudmersen, B. F. Runge, R. A. O'Brien. Details of methods employed for the standardization of antidysentery serum have already been published [see this Bulletin, Vol. 22, p. 22, SUDMERSEN, RUNGE & O'BRIEN, ] and the standard " toxin " and " anti-toxin " described. Commencing with their initial standards, the authors have now prepared a second toxin-3 A-which has been titrated against a test serum S. : R. A. O'Brien, B. F. Runge. The titration of antidysenteric sera has not yet attained the accuracy of methods used for antidiphtheritic and antitetanic sera. This is partly due to wide variation in susceptibility of individual mice and partly to difficulty in obtaining a toxin sufficiently concentrated or in a physical state suitable for intravenous injection. It has been shown, likewise, that the substitution of rabbits Cited by: 3. The dysentery dysentery Subject Category: Diseases, Disorders, and Symptoms see more details toxin is combined with the serum according to a definite rule of multiple proportion. The combining power of the several fluid toxins was generally the same.
The Standardization of Anti-Dysentery (Shiga) Serum: II*. Coronavirus: Find the latest articles and preprints The Standardization of Anti-Dysentery (Shiga) Serum: II*. O'Brien RA, Runge BF. British Journal of Experimental Pathology, 01 Apr , 6(2): PMCID: PMC Europe PMC is an ELIXIR Core Data Resource Learn more >. Europe PMC is a service of the Europe PMC Funders' Group, in partnership with the European Bioinformatics Institute; and in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine (NCBI/NLM).It includes content provided to the PMC International archive by participating publishers. Seven antidysenteric sera were standardized against the international dry standard serum, using the in vitro precipitation and the in vivo mouse test. For the precipitation test, poly-saccharide was extracted from 7-day cultures of Shiga's dysentery bacillus in per cent, glucose broth, diluted 1/1, , and mixed with an equal quantity of serum in different dilutions, according to the. Every case of dysentery in this series was a f positive bacillary case in the sense that (a) an undis- puted dysentery-causing bacillus was obtained from its stools, or (b) its blood-serum agglutinated not only a standardised emulsion of a dysentery organism, but also an identically similar organism found in the stools of another patient in the.
Bacillary Dysentery. Bacillary dysentery should be considered in any patient with acute diarrheal illness associated with toxemia and systemic symptoms, particularly when the illness lasts longer than 48 hours, and when intrafamily spread occurs with an interval of 1 to 3 days between cases, fever is present, or blood or mucus is seen in stool. The Standardization of Anti-Dysentery (Shiga) Serum: II * R. A. O'Brien and B. F. Runge * The work reported in this paper will form a report to the League of Nations Standardization Committee. A dysentery is a form of gastroenteritis that is characterized by frequent and uncontrolled bowel movements. It is mostly marked by a few symptoms of Diarrhoea. But in this case, the patients may experience watery stools along with blood. Middle and low-income countries show higher incidence rates of dysentery. The National book depot. Dysentery in the Mediterranean Expeditionary, Oxford Journals Medicine QJM: An International Journal of Medicine Volume os, Issue 44 Pp. We aimed to.